Enrolling Dermatology Trials
Pain in Hidradenitis Suppurativa (HS): Outcome Metrics and Improvement in Quality of Life
We are currently seeking participants for a research study about pain in hidradenitis suppurativa (HS).
This 16-week study will include 2 in-person visits with additional remote visits. The study team will ask you to do the following:
- To have your skin examined
- To fill out questionnaires that ask about your quality of life and your pain
- To have some photos taken of your skin lesions
- To have a blood sample drawn
- To undergo quantitative sensory testing (QST) on the back of your hand and on select HS lesions
Inclusion criteria
- Dermatologist-confirmed diagnosis of HS
- Ongoing HS activity
- Age ≥16 years – 80 years
- Ability to understand and read English in order to read questionnaires
- Reliable internet and telephone access
- Stated willingness to stay on the same HS disease-modifying therapy over the course of the study
Exclusion criteria
- Medical conditions other than HS causing chronic pain
- Medical conditions causing neuropathy such as diabetic neuropathies
- Change in systemic HS disease-modifying therapy in the 4 weeks prior to inclusion (for non-biologic), or 8 weeks prior (for biologics)
- New prescription of a sedative, NMDA receptor agonist, eugeroic antidepressant, or scheduled opioid within 4 weeks prior to inclusion
For more information on this study please contact Meron Siira.
Improving Clinical Trial Recruitment and Outcome Measures in Bullous Pemphigoid
The overall objective of this observational clinical trial is to better characterize changes in disease activity, pruritus in a prospective manner and capture patient-reported outcomes that could be utilized to design better therapeutic trials for bullous pemphigoid. A unique Teledermatology platform is being piloted to improve patient recruitment and retention. These data will provide much-needed information related to the natural disease history of bullous pemphigoid and specific measurements for future clinical trials.
A Study to Investigate the Use of Benralizumab in Patients With Bullous Pemphigoid
The purpose of this study is to investigate the use of benralizumab is effective in the treatment of patients symptomatic Bullous Pemphigoid (BP).