Congratulations to the Ortlund lab on their publication, "Temporal dynamics of the multi-omic response to endurance exercise training," in Nature. This paper was part of a group of papers released May 1 in Nature discussing the findings of the Molecular Transducers of Physical Activity Consortium (MoTrPAC), a ten-year effort launched in 2016 by the National Institutes of Health (NIH) to uncover how exercise improves and maintains our health at the molecular level. Dr. Kristal Maner-Smith, Dr. Zhenxin Hou, and Dr. Snow Galbin/Liu and Dr. Chih-yu Chen performed data collection and analysis for this study. The work was also featured on the journal's May 2 cover and in a Nature news feature.
Georgia Institute of Technology bioanalytical chemist Facundo Fernández, PhD, and Emory University biochemist Eric Ortlund, PhD, lead one of the Consortium’s Chemical Analysis Sites, joining researchers across the country to collect and translate data from animals and more than 2,000 volunteers into comprehensive maps of the cellular changes throughout the body in response to exercise.
MoTrPAC’s latest group of papers details data from studies in rats, uncovering how endurance exercise affects biological molecules and “all tissues of the body,” as well as tissues and gene expression, along with striking tissue differences between male and female organisms.